Scientific Presentations

The natural human antibody PAT-SM6 specifically targets and kills primary multiple myeloma cells by induction of apoptosis and complement activation, 2011, Rasche, L., Hensel, F., Brandlein, S., Workshop: The New ParadIgM - IgM from Bench to Clinic, November 15-16, Frankfurt, Germany

Preliminary results from a first-in-human trial of PAT-SM6 IgM in patients with melanoma, 2011, Greenwood, D., Hedt, A., Brandlein, S., Hensel, F., Workshop: The New ParadIgM - IgM from Bench to Clinic, November 15-16, Frankfurt, Germany

Upstream and downstream challenges of clinical production of a human IgM antibody therapeutic, 2011, Ultee, M., Workshop: The New ParadIgM - IgM from Bench to Clinic, November 15-16, Frankfurt, Germany

Characterization of IgM-antigen interactions using fluorescence detection in the analytical ultracentrifuge, 2011, Mok Y-F, Rosens Z., Mulhern, T.D., Hatters, D,M., Howlett, G.I., Workshop: The New ParadIgM - IgM from Bench to Clinic, November 15-16, Frankfurt, Germany

Upstream and downstream challenges of clinical production of a human IgM antibody therapeutic, 2011, Conner, M., Ultee, M., BioProcess International Conference and Exhibition, Oct 31- Nov 4, Long Beach, CA, United States

Natural human IgM antibodies targeting primary multiple myeloma, 2011, Rasche, L., Dull, J., Morgner, C., Hensel, F., Einsele, H., Annual Conference of the German Society for Haematology and Oncology (DGHO). Sept 30- Oct 2, Basel, Switzerland

The natural IgG antibody PAT-BA4 binds to a tumour-specific form of TAF15 and inhibits tumour cell adhesion and movement, 2010, Vollmers H.P., Schatz N, Ruckl K, Hensel F, Brandlein S, American Association for Cancer Research 100th Annual Meeting, April 17-21, Washington, United States

New cancer specific targets defined by natural human monoclonal antibodies, 2010, Schatz N., Human Antibodies and Hybridomas Conference, April 14-16, Porto, Portugal

TAF15, a new tumorspecific antigen defined by the natural human monoclonal IgG antibody PAT-BA4, 2009, Schatz N, Brandlein s, Ruckl K, Hensel F, Vollmers H.P., American Association for Cancer Research 100th Annual Meeting, April 18-22, Denver, United States

IgM antibodies for natural high avidity to cancer targets, 2009, Power, B., 3rd International Symposium on Antibody Engineering and Antibody-based Therapeutics, March 2-5, Taipei, Taiwan.

Characterisation of recombinant full-length and fragments of a lipoptotic natural human IgM Antibody, 2009, C.G. Hosking, T.D. Mulhern, G.J. Howlett, P.A. O’Donnell, L. Udabage, B.C. Tan, T. Ryan, F. Hensel, H.P. Vollmers, L.L Ilag, B.E. Power. The 34th Lorne Conference on Protein Structure and Function, February 8-12, Lorne, Victoria, Australia

Recombinant PAT-SM6 human antibodies as therapeutic agents for cancer therapy, 2009, L. Udabage, B.C. Tan, C.G. Hosking, F. Hensel, H.P. Vollmers, L.L Ilag, B.E. Power. The 34th Lorne Conference on Protein Structure and Function, February 8-12, Lorne, Victoria, Australia

A glyco-variant of GRP78 on malignant melanoma as a target for human antibody treatment, 2008, Vollmers HP, Mueller K, Brändlein S, Annual American Association for Cancer Research Meeting, April 12-16, San Diego, CA, USA

Natural IgG antibodies as therapeutic agents for carcinoma and melanoma, 2008, Brändlein S, Schatz N, Eckstein M, Vollmers HP, Annual American Association for Cancer Research Meeting, April 12-16, San Diego, CA, USA

Cancer immunotherapy with cocktails of human monoclonal antibodies, 2008, Rasche L, Brändlein S, Vollmers HP, 28. Deutscher Krebskongress, February 20-23, Berlin, Germany

IgM Purification: The Next Generation, 2008, Gagnon P, Hensel F, Richieri R,  13th Waterside Monoclonal Conference, February 4-6, 2008, Miam, FL (USA)

The human antibody SAM-6 defines a new tumor-specific variant of the heat shock protein GRP78, 2007, Brändlein S, Rauschert N, Rasche L, Hensel F, Vollmers HP, Human Antibodies and Hybridomas Conference, October 29-31, Milan, Italy

A new tumor-specific variant of the heat shock protein GRP78 as target for antibody therapy, 2007, Vollmers HP, Rauschert N, Rasche L, Brändlein S, AACR-NCI-EORTC International Conference, Molecular Targets and Cancer Therapeutics October 22-26, 2007, San Francisco, CA (USA)

The human lipotoxic antibody SAM-6 targets a new variant of the heat shock protein GRP78, 2007, Rauschert N, Brändlein S, Holzinger E, Hensel F, Vollmers HP, AACR Annual Meeting, April 14-18, Los Angeles, CA (USA)

Recent advances in the purification of IgM monoclonal antibodies, 2007, Gagnon P, Hensel F, Andrews P, Richieri R, Third Wilbio Conference on Purification of Biological Products, September 24-26, Waltham, MA (USA)

 
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