Click on the links below to view the Scientific Publications:

2008

Beutner U, Lorenz U, Illert B, Rott L, Timmermann W, Vollmers HP, Muller-Hermelink HK, Thiede A, and Ulrichs K. Neoadjuvant therapy of gastric cancer with the human monoclonal IgM antibody SC-1: Impact on the immune system, Oncol Rep. 19(3), 761-769 (2008).

Rauschert N, Brändlein S, Holzinger E, Hensel F, Müller-Hermelink HK, Vollmers HP. A new tumor-specific variant of GRP-78 as target for antibody-based therapy, Lab Invest. 88(4), 375-86, (2008).

Gagnon P, Hensel F, Richieri R. Purification of IgM Monoclonal Antibodies, BioPharm Int. March supplement, pp. 26-36 (2008).

2007

Brändlein S, Rauschert N, Rasche L, Dreykluft A, Hensel F, Conzelmann E, Müller-Hermelink HK, Vollmers HP. The human IgM antibody SAM-6 induces tumor-specific apoptosis with oxidized low-density lipoprotein, Mol Cancer Ther. 6(1), 326-333 (2007).

Vollmers HP, Brändlein S. Natural antibodies and cancer, J Autoimmun 29(4), 295-302 (2007).

Vollmers HP, Brändlein S. Tumors: too sweet to remember?, Mol Cancer 6,78 (2007).

2006

Vollmers HP, Brändlein S. Natural IgM antibodies: from parias to parvenus, Histol Histopathol. 21(12):1355-1366 (2006).

Vollmers HP, Brändlein S. Natural IgM antibodies: the orphaned molecules in immune surveillance, Adv Drug Deliv Rev. 58(5-6):755-765 (2006).

2005

Vollmers HP, Brändlein S. The "early birds": Natural IgM antibodies and immune surveillance, Histol Histopathol. 20(3):927-937 (2005).

Vollmers HP, Brändlein S. Death by Stress: Natural IgM-induced apoptosis, Methods Find Exp Clin Pharmacol. 27(3):185-91 (2005).

Illert B, Otto C, Vollmers HP, Hensel F, Thiede A,Timmermann W. Human antibody SC-1 reduces disseminated tumor cells in nude mice with human gastric cancer, Oncol Rep., 13(4),765-770 (2005).

2004

Brändlein S, Eck, M, Strobel, P, Wozniak, E, Müller-Hermelink HK, Hensel F, Vollmers HP. PAM-1, a natural human IgM antibody as new tool for detection of breast and prostate precursors, Hum Antibodies, 13(4), 97-104 (2004).

Pohle T, Brändlein S, Ruoff N, Müller-Hermelink HK, Vollmers HP. Lipoptosis: tumor-specific cell death by antibody-induced intracellular lipid accumulation, Cancer Res, 64(11), 3900-3906 (2004).  

Brändlein S, Vollmers HP. Natural IgM antibodies, the ignored weapons in tumour immunity, Histol Histopathol, 19(3), 897-905 (2004).

Brändlein S, Pohle T, Vollmers C, Wozniak E, Ruoff N, Müller-Hermelink, HK. Vollmers H.P. CFR-1 receptor as target for tumor-specific apoptosis induced by the natural human monoclonal antibody PAM-1. Oncol Rep., 11(4), 777-784 (2004).

2003

Brändlein S, Pohle T, Ruoff N, Wozniak E, Müller-Hermelink HK, Vollmers HP. Natural IgM antibodies and immunosurveillance mechanisms against epithelial cancer cells in humans. Cancer Res., 63(22), 7995-8005 (2003).

Brändlein S, Beyer I, Eck M, Bernhardt W, Hensel F, Müller-Hermelink HK, Vollmers HP. CFR-1, a new marker for precancerous epithelial lesions defined by the human monoclonal antibody PAM-1, Cancer Res 63(9), 2052-2061 (2003). 

2002

Vollmers HP and Brändlein S. Nature´s best weapons to fight cancer, Revival of human monoclonal IgM antibodies, Hum Antibodies 11(4), 131-142 (2002).

Brändlein S, Lorenz J, Ruoff N, Hensel F, Beyer I, Mueller J, Neukam K, Illert B, Eck M, Mueller-Hermelink HK, Vollmers HP. Human monoclonal IgM antibodies with apoptotic activity isolated from cancer patients, Hum. Antibodies 11(4), 107-119 (2002).

2001

Hermann R, Hensel F, Mueller E, Keppler M, Souto-Carneiro MM, Brändlein S, Müller-Hermelink HK, and Vollmers HP. Deactivation of regulatory proteins hnRNP A1 and A2 during SC-1 induced apoptosis, Hum. Antibodies, 10(2), 83-90 (2001).  

Hensel F, Herrmann R, Brändlein S, Krenn V, Schmausser B, Geis S, Müller-Hermelink HK, Vollmers HP. Regulation of the New Coexpressed CD55 (Decay Accelerating Factor) receptor on stomach carcinoma cells involved in antibody SC-1-induced apoptosis , Lab. Invest., 81(11), 1553-1563 (2001).

Hensel F, Brändlein S, Eck M, Schmidt K, Krenn V, Kloetzer A, Bachi A, Mann M, Müller-Hermelink HK, and Vollmers HP. A novel proliferation-associated variant of cfr-1 defined by a human monoclonal antibody, Lab. Invest., 81(8), 1097-1108 (2001).

2000

Vollmers HP, Timmermann W, Hensel F, Illert B, Thiede A and Müller-Hermelink HK. [Adjuvant immunotherapy of stomach carcinoma with antibody-induced apoptosis.], Zentralbl Chir., 125, Suppl 1:37-40 (2000).

1999

Hensel F, Hermann R, Schubert C, Abé N, Schmidt K, Franke A, Shevchenko A, Mann M, Müller-Hermelink HK, and Vollmers HP. Characterisation of glycosylphosphatidylinositol linked molecule CD55/Decay accelerating factor as the receptor for antibody SC-1-induced apoptosis, Cancer Res., 59(20), 5299-5306 (1999).

Hensel F, Knoerr C, Hermann R, Krenn V, Müller-Hermelink HK, and Vollmers HP. Mitogenic autoantibodies in Helicobacter pylori-associated stomach cancerogenesis, Int. J. Cancer, 81(2), 229-235 (1999).

1998

Vollmers HP, Hensel F, Hermann R, Daemmrich J, Wozniak E, Gessner P, Herrmann B, Zimmermann U and Müller-Hermelink HK. Tumor-specific apoptosis by the human monoclonal antibody SC-1: A new therapeutical approach for stomach cancer, Oncol Rep., 5(1), 35-40 (1998).

Vollmers HP, Zimmermann U, Krenn V, Timmermann W, Illert B, Hensel F, Hermann R, Thiede A, Wilhelm M, Rueckle-Lanz H, Reindl L and Mueller-Hermelink HK. Adjuvant therapy for gastric adenocarcinoma with the apoptosis-inducing human monoclonal antibody SC-1: first clinical and histopathological results, Oncol. Rep., 5(3), 549-552 (1998).

1997

Vollmers HP, Däemmrich J, Hensel F, Ribbert H, Meyer-Bahlburg A, Ufken-Gaul T, v.Korff M and Müller-Hermelink HK. Differential expression of apoptosis receptors on diffuse and intestinal type stomach carcinoma, Cancer, 79(3), 433-440 (1997).

1996

Vollmers HP, Wozniak E, Stepien-Botsch E, Zimmermann U, Müller-Hermelink, HK. A rapid method for purification of monoclonal human IgM from mass culture. Hum Antibodies Hybridomas, 7(1), 37-41 (1996)

1995

Vollmers HP, Däemmrich J, Ribbert H, Wozniak E, Müller-Hermelink HK. Apoptosis of stomach carcinoma cells induced by a human monoclonal antibody, Cancer 76(4), 550-558 (1995).

Däemmrich J, Vollmers HP, Heider KH, Müller-Hermelink HK. Importance of different CD44v6 expression in human gastric intestinal and diffuse type cancers for metastatic lymphogenic spreading., J Mol Med 73(8), 395-401 (1995).

1994

Vollmers HP, Däemmrich J, Ribbert H, Grassel S, Debus S, Heesemann J, Müller-Hermelink HK. Human monoclonal antibodies from stomach carcinoma patients react with Helicobacter pylori and stimulate stomach cancer cells in vitro, Cancer 74(5), 1525-1532 (1994).

1990

Faller G, Vollmers HP, Weiglein I, Marx A, Zink C, Pfaff M, Müller-Hermelink, H. HAB-1, a new heteromyeloma for continuous production of human monoclonal antibodies, Br J Cancer, 62(4), 595-8 (1990).

Pfaff M, O'Connor R, Vollmers HP, Müller-Hermelink H. Human monoclonal antibody against a tissue polypeptide antigen-related protein from a patient with a signet-ring cell carcinoma of the stomach, Cancer Res, 50(16), 5192-8 (1990).

1989

Vollmers HP, O'Connor R, Mueller J, Kirchner T, Müller-Hermelink HK. SC-1, a functional human monoclonal antibody against autologous stomach carcinoma cells, Cancer Res. 49(9), 2471-2476 (1989).

1985

Goodman SL, Vollmers HP, Birchmeier W. Control of cell locomotion: perturbation with an antibody directed against specific glycoproteins, Cell 41(3), 1029-38 (1985).

Vollmers, HP, Imhof BA, Wieland I, Hiesel A, Birchmeier W. Monoclonal antibodies NORM-1 and NORM-2 induce more normal behaviour of tumor cells in vitro and reduce tumor growth in vivo, Cell 40(3), 547-57 (1985).

1984

Vollmers HP, Imhof BA, Braun S, Waller CA, Schirmacher V, Birchmeier A. Monoclonal antibodies which prevent experimental lung metastases. Interference with the adhesion of tumour cells to laminin. FEBS Lett, 172(1), 17-20 (1984).

1983

Imhof BA, Vollmers HP, Goodman SL, Birchmeier W. Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody. Cell, 35 (3 Pt 2), 667-75 (1983).

Vollmers HP, Birchmeier W. Monoclonal antibodies that prevent adhesion of B 16 melanoma cells and reduce metastases in mice: crossreaction with human tumor cells. Proc Natl Acad Sci USA, 80(22), 6863-7 (1983).

Vollmers HP, Birchmeier W. Monoclonal antibodies that inhibit adhesion of B 16 melanoma cells in vitro and block lung metastasis in vivo. Proc Natl Acad Sci USA, 80(12), 3729-33 (1983).

1979

Gotze D, Vollmers HP. Reactivity of monoclonal antibodies specific for H-2 antigenic determinants with cells of wild mice. Immunol Rev, 47, 207-18 (1979).